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Bubonic Plague of Justinian Trivia Questions

How much do you really know about Bubonic Plague of Justinian? Below are 8 true or false statements. Click each one to reveal the answer and explanation.

1.

The Plague of Justinian was confined only to Constantinople and never spread to other parts of Europe.

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Easy
✗ FALSE

The plague spread throughout the Mediterranean, reaching Italy, Gaul, and even Britain via trade routes.

2.

The Plague of Justinian was named after Emperor Justinian, who died from the disease himself.

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Easy
✗ FALSE

Justinian contracted the plague but survived; he died later from natural causes. The plague is named for his reign.

3.

The Plague of Justinian helped end the Roman Empire's reunification efforts under Emperor Justinian.

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Medium
✓ TRUE

The plague devastated the Byzantine army and economy, halting Justinian's campaigns to reconquer the Western Roman Empire.

4.

The Plague of Justinian was caused by the same bacterium that caused the Black Death, Yersinia pestis.

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Medium
✓ TRUE

DNA analysis of ancient skeletons confirms Yersinia pestis caused both the Justinianic Plague and the Black Death.

5.

Modern vaccines for the bubonic plague were developed directly from studying the Plague of Justinian.

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Medium
✗ FALSE

Vaccines were developed in the 19th and 20th centuries using modern strains, not from the Justinianic Plague.

6.

The Plague of Justinian is estimated to have killed up to 100 million people globally.

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Hard
✓ TRUE

Some historians estimate 25–100 million deaths, though modern scholars debate the figures due to sparse records.

7.

The Plague of Justinian ended because the population developed permanent immunity to the bacterium.

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Hard
✗ FALSE

Immunity was temporary and the plague returned in waves. It likely faded due to climate changes and rodent population shifts.

8.

The Plague of Justinian may have contributed to the rise of Islam by weakening the Byzantine and Persian empires.

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Hard
✓ TRUE

Both empires were exhausted by plague and war, making them vulnerable to the rapid Arab conquests in the 7th century.

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