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Sydney Brenner Trivia Questions

How much do you really know about Sydney Brenner? Below are 8 true or false statements. Click each one to reveal the answer and explanation.

1.

Brenner died at age 89 after falling into a volcano during a field trip to Hawaii.

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Easy
✗ FALSE

He died peacefully at home in Singapore in 2019 at age 92. The volcano story is an absurd myth.

2.

Brenner's first major paper was on the genetic control of flower color in petunias.

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Easy
✗ FALSE

His early work focused on bacterial genetics and phage biology, not plants. Flower color research is associated with Gregor Mendel.

3.

Brenner won the Nobel Prize for his discovery of the structure of DNA.

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Medium
✗ FALSE

He won the 2002 Nobel Prize in Physiology or Medicine for discoveries in organ development and programmed cell death, not DNA structure.

4.

As a child in South Africa, Brenner built a chemistry lab in his parents' garage.

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Medium
✓ TRUE

Sydney Brenner was a science prodigy; at age 10, he set up a small chemistry laboratory in his parents' garage in South Africa, demonstrating his early passion for research.

5.

Sydney Brenner was a key figure in the Human Genome Project, helping to establish the Sanger Institute which led the British sequencing effort.

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Medium
✓ TRUE

He played a pivotal role in initiating the UK's Human Genome Project contribution and was instrumental in creating the Wellcome Trust Sanger Institute, the primary British sequencing center.

6.

Sydney Brenner named the nematode C. elegans as a model organism for studying development and neurobiology.

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Medium
✓ TRUE

Brenner pioneered the use of C. elegans in the 1960s, revolutionizing genetics by linking cell lineage to gene function.

7.

Brenner discovered the first restriction enzyme used for DNA cloning.

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Hard
✗ FALSE

That credit goes to Hamilton Smith and Werner Arber; Brenner worked on messenger RNA and the genetic code, not restriction enzymes.

8.

Brenner coined the term 'codon' to describe the three-nucleotide unit of the genetic code.

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Hard
✓ TRUE

He introduced 'codon' in a 1961 paper with Crick and others, defining the triplet code that specifies amino acids.

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